See the Science
Capsaicin
Delivers deep warming relief that helps ease knee discomfort.
Supports mobility during walking, stairs, and daily movement.
Builds effect with consistent use for steady comfort over days.
Menthol
Provides instant cooling comfort for an immediate easing sensation.
Soothes soreness and balances capsaicin’s warmth for a pleasant cool–warm feel.
Helps you feel ready to move sooner after application.
Ginger
Offers natural soothing support for stiff, overworked knees.
Comforts during daily activity—walking, standing, and light exercise.
Complements other botanicals for a well‑rounded calming effect.
Wormwood (Artemisia absinthium)
Targets local aching and tenderness for noticeable comfort.
Supports ease of movement when getting up, down, or changing direction.
Works synergistically with warming and cooling agents for balanced relief.
Processed Aconite (Fuzi)
Provides deep, warming comfort that relaxes tense, tight areas around the knee.
Enhances overall soothing when combined with other botanicals in the patch.
Ideal for days when knees feel heavy, cold, or overworked.
Adhesion & Delivery — Borneol + Azone (Laurocapram)
Helps the patch stay put comfortably during daily wear.
Optimizes delivery of key botanicals through the skin for effective, targeted comfort.
Supports consistent, long‑lasting relief without mess or frequent reapplication.
Patch Format (Why a Patch?)
Steady, time‑released comfort right where you need it.
No mess, no transfer—easy to wear under clothing.
Designed for on‑the‑go relief at work, school, or training.
For educational product description purposes only. Individual experience may vary.
References
Deal CL, Schnitzer TJ, et al. Treatment of arthritis with topical capsaicin: a double‑blind trial. Clin Ther. 1991;13(3):383‑395. PubMed
Tshering G, Posadzki P, Kongkaew C. Efficacy and safety of topical capsaicin in the treatment of osteoarthritis pain: a systematic review and meta‑analysis. Phytother Res. 2024. Wiley | PubMed
Topp RV, Brosky JA Jr, Pieschel D. The effect of either topical menthol or a placebo on functioning and knee pain among patients with knee OA. J Geriatr Phys Ther. 2013;36(2):92‑99. PubMed
Altman RD, Marcussen KC. Effects of a ginger extract on knee pain in patients with osteoarthritis. Arthritis Rheum. 2001;44(11):2531‑2538. PubMed
Bartels EM, et al. Efficacy and safety of ginger in osteoarthritis patients: a meta‑analysis of randomized placebo‑controlled trials. Osteoarthritis Cartilage. 2015;23(1):13‑21. Full text | PubMed
Basiri Z, et al. Topical effects of Artemisia absinthium ointment and liniment vs piroxicam gel in knee osteoarthritis: randomized double‑blind controlled trial. Iran J Med Sci. 2017;42(6):524‑531. PMC
Wu Y, et al. Aconiti lateralis radix praeparata total alkaloids exert anti‑rheumatoid arthritis effects via NF‑κB and JAK/STAT pathways. Front Pharmacol. 2022;13:980229. Full text | PubMed
Tang M, et al. Role of borneol as enhancer in drug formulation: a review. J Pharm Anal. 2024. PubMed | ScienceDirect
Kulkarni M, et al. Borneol: a promising monoterpenoid in enhancing drug delivery. Curr Drug Deliv. 2021;18(9):1285‑1302. PubMed
Sugibayashi K, et al. Mechanism of skin penetration‑enhancing effect by laurocapram (Azone). J Pharm Sci. 1992;81(7):610‑614. PubMed | Full text
Ogiso T, et al. Enhancement of percutaneous absorption by laurocapram (Azone). Chem Pharm Bull (Tokyo). 1992;40(1):203‑207. PubMed
Haque T, et al. Chemical enhancers: a simplistic way to modulate barrier properties of the stratum corneum. Adv Pharm Bull. 2018;8(2):169‑179. PMC
Pastore MN, et al. Transdermal patches: history, development and pharmacology. Br J Pharmacol. 2015;172(9):2179‑2209. PMC
Paudel KS, et al. Challenges and opportunities in dermal/transdermal delivery. Ther Deliv. 2010;1(1):109‑131. PMC
Last updated: August 27, 2025.